Nitric Oxide-induced Activation of the Type 1 Ryanodine Receptor Is Critical for Epileptic Seizure-induced Neuronal Cell Death

Status epilepticus (SE) is a life-threatening emergency that can cause neurodegeneration with debilitating neurological disorders. However, the mechanism by which convulsive SE results in neurodegeneration is not fully understood. It has been shown that epileptic seizures produce markedly increased...

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Vydáno v:EBioMedicine
Hlavní autoři: Mikami, Yoshinori, Kanemaru, Kazunori, Okubo, Yohei, Nakaune, Takuya, Suzuki, Junji, Shibata, Kazuki, Sugiyama, Hiroki, Koyama, Ryuta, Murayama, Takashi, Ito, Akihiro, Yamazawa, Toshiko, Ikegaya, Yuji, Sakurai, Takashi, Saito, Nobuhito, Kakizawa, Sho, Iino, Masamitsu
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier 2016
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5049986/
https://ncbi.nlm.nih.gov/pubmed/27544065
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2016.08.020
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