Nitric Oxide-induced Activation of the Type 1 Ryanodine Receptor Is Critical for Epileptic Seizure-induced Neuronal Cell Death

Status epilepticus (SE) is a life-threatening emergency that can cause neurodegeneration with debilitating neurological disorders. However, the mechanism by which convulsive SE results in neurodegeneration is not fully understood. It has been shown that epileptic seizures produce markedly increased...

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Detalhes bibliográficos
Publicado no:EBioMedicine
Main Authors: Mikami, Yoshinori, Kanemaru, Kazunori, Okubo, Yohei, Nakaune, Takuya, Suzuki, Junji, Shibata, Kazuki, Sugiyama, Hiroki, Koyama, Ryuta, Murayama, Takashi, Ito, Akihiro, Yamazawa, Toshiko, Ikegaya, Yuji, Sakurai, Takashi, Saito, Nobuhito, Kakizawa, Sho, Iino, Masamitsu
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5049986/
https://ncbi.nlm.nih.gov/pubmed/27544065
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2016.08.020
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