Protocadherin-1 Localization and Cell-Adhesion Function in Airway Epithelial Cells in Asthma

BACKGROUND: The asthma gene PCDH1 encodes Protocadherin-1, a putative adhesion molecule of unknown function expressed in the airway epithelium. Here, we characterize the localization, differential expression, homotypic adhesion specificity and function of PCDH1 in airway epithelial cells in asthma....

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Détails bibliographiques
Publié dans:PLoS One
Auteurs principaux: Faura Tellez, Grissel, Willemse, Brigitte W. M., Brouwer, Uilke, Nijboer-Brinksma, Susan, Vandepoele, Karl, Noordhoek, Jacobien A., Heijink, Irene, de Vries, Maaike, Smithers, Natalie P., Postma, Dirkje S., Timens, Wim, Wiffen, Laura, van Roy, Frans, Holloway, John W., Lackie, Peter M., Nawijn, Martijn C., Koppelman, Gerard H.
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2016
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5049773/
https://ncbi.nlm.nih.gov/pubmed/27701444
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0163967
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