SIRT1/FoxO3 axis alteration leads to aberrant immune responses in bronchial epithelial cells

Inflammation and ageing are intertwined in chronic obstructive pulmonary disease (COPD). The histone deacetylase SIRT1 and the related activation of FoxO3 protect from ageing and regulate inflammation. The role of SIRT1/FoxO3 in COPD is largely unknown. This study evaluated whether cigarette smoke,...

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Detalhes bibliográficos
Publicado no:J Cell Mol Med
Main Authors: Di Vincenzo, Serena, Heijink, Irene H., Noordhoek, Jacobien A., Cipollina, Chiara, Siena, Liboria, Bruno, Andreina, Ferraro, Maria, Postma, Dirkje S., Gjomarkaj, Mark, Pace, Elisabetta
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2018
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5867095/
https://ncbi.nlm.nih.gov/pubmed/29411515
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.13509
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