Smad gene expression in pulmonary fibroblasts: indications for defective ECM repair in COPD

BACKGROUND: Chronic Obstructive Pulmonary Disease (COPD) is characterized by defective extracellular matrix (ECM) turnover as a result of prolonged cigarette smoking. Fibroblasts have a central role in ECM turnover. The TGFβ induced Smad pathway provides intracellular signals to regulate ECM product...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Zandvoort, Andre, Postma, Dirkje S, Jonker, Marnix R, Noordhoek, Jacobien A, Vos, Johannes TWM, Timens, Wim
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: BioMed Central 2008
Gaiak:
Research
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2613883/
https://ncbi.nlm.nih.gov/pubmed/19087346
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1465-9921-9-83
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