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Protocadherin-1 Localization and Cell-Adhesion Function in Airway Epithelial Cells in Asthma

BACKGROUND: The asthma gene PCDH1 encodes Protocadherin-1, a putative adhesion molecule of unknown function expressed in the airway epithelium. Here, we characterize the localization, differential expression, homotypic adhesion specificity and function of PCDH1 in airway epithelial cells in asthma....

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Faura Tellez, Grissel, Willemse, Brigitte W. M., Brouwer, Uilke, Nijboer-Brinksma, Susan, Vandepoele, Karl, Noordhoek, Jacobien A., Heijink, Irene, de Vries, Maaike, Smithers, Natalie P., Postma, Dirkje S., Timens, Wim, Wiffen, Laura, van Roy, Frans, Holloway, John W., Lackie, Peter M., Nawijn, Martijn C., Koppelman, Gerard H.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5049773/
https://ncbi.nlm.nih.gov/pubmed/27701444
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0163967
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