Nitrotriazole-based acetamides and propanamides with broad spectrum antitrypanosomal activity

3-Nitro-1H-1,2,4-triazole-based acetamides bearing a biphenyl- or a phenoxyphenyl moiety have shown remarkable antichagasic activity both in vitro and in an acute murine model, as well as substantial in vitro antileishmanial activity but lacked activity against human African trypanosomiasis. We have...

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Xehetasun bibliografikoak
Argitaratua izan da:Eur J Med Chem
Egile Nagusiak: Papadopoulou, Maria V., Bloomer, William D., Rosenzweig, Howard S., Wilkinson, Shane R., Szular, Joanna, Kaiser, Marcel
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Editions Scientifiques Elsevier 2016
Gaiak:
Research Paper
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5049494/
https://ncbi.nlm.nih.gov/pubmed/27543881
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejmech.2016.08.002
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