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Antitrypanosomal activity of 5-nitro-2-aminothiazole-based compounds

A small series of 5-nitro-2-aminothiazole-based amides containing arylpiperazine-, biphenyl- or aryloxyphenyl groups in their core were synthesized and evaluated as antitrypanosomatid agents. All tested compounds were active or moderately active against Trypanosoma cruzi amastigotes in infected L6 c...

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Detalhes bibliográficos
Publicado no:Eur J Med Chem
Main Authors: Papadopoulou, Maria V., Bloomer, William D., Rosenzweig, Howard S., Wilkinson, Shane R., Szular, Joanna, Kaiser, Marcel
Formato: Artigo
Idioma:Inglês
Publicado em: Editions Scientifiques Elsevier 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4876673/
https://ncbi.nlm.nih.gov/pubmed/27092415
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejmech.2016.04.010
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