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Novel 3-Nitro-1H-1,2,4-triazole-based Aliphatic and Aromatic Amines as anti-Chagasic Agents

A series of novel 2-nitro-1H-imidazole- and 3-nitro-1H-1,2,4-triazole-based aromatic and aliphatic amines were screened for anti-trypanosomal activity and mammalian cytotoxicity by the Drugs for Neglected Diseases initiative (DNDi). Out of 42 compounds tested, eighteen 3-nitro-1,2,4-triazoles and on...

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Detalhes bibliográficos
Main Authors: Papadopoulou, Maria V., Bourdin Trunz, Bernadette, Bloomer, William D., McKenzie, Caroline, Wilkinson, Shane R., Prasittichai, Chaiya, Brun, Reto, Kaiser, Marcel, Torreele, Els
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3258117/
https://ncbi.nlm.nih.gov/pubmed/22023653
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm201215n
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