Patient survival and tumor characteristics associated with CHEK2:p.I157T – findings from the Breast Cancer Association Consortium

BACKGROUND: P.I157T is a CHEK2 missense mutation associated with a modest increase in breast cancer risk. Previously, another CHEK2 mutation, the protein truncating c.1100delC has been associated with poor prognosis of breast cancer patients. Here, we have investigated patient survival and character...

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Detaylı Bibliyografya
Yayımlandı:Breast Cancer Res
Asıl Yazarlar: Muranen, Taru A., Blomqvist, Carl, Dörk, Thilo, Jakubowska, Anna, Heikkilä, Päivi, Fagerholm, Rainer, Greco, Dario, Aittomäki, Kristiina, Bojesen, Stig E., Shah, Mitul, Dunning, Alison M., Rhenius, Valerie, Hall, Per, Czene, Kamila, Brand, Judith S., Darabi, Hatef, Chang-Claude, Jenny, Rudolph, Anja, Nordestgaard, Børge G., Couch, Fergus J., Hart, Steven N., Figueroa, Jonine, García-Closas, Montserrat, Fasching, Peter A., Beckmann, Matthias W., Li, Jingmei, Liu, Jianjun, Andrulis, Irene L., Winqvist, Robert, Pylkäs, Katri, Mannermaa, Arto, Kataja, Vesa, Lindblom, Annika, Margolin, Sara, Lubinski, Jan, Dubrowinskaja, Natalia, Bolla, Manjeet K., Dennis, Joe, Michailidou, Kyriaki, Wang, Qin, Easton, Douglas F., Pharoah, Paul D. P., Schmidt, Marjanka K., Nevanlinna, Heli
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BioMed Central 2016
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5048645/
https://ncbi.nlm.nih.gov/pubmed/27716369
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13058-016-0758-5
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