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Studies on a novel series of acyl ester prodrugs of prostaglandin F2 alpha.

A novel series of prostaglandin F2 alpha (PGF2 alpha) prodrugs, with acyl ester groups at the 9, 11, and 15 positions, was prepared in order to design clinically acceptable prostaglandins for treating glaucoma. Studies involving isolated esterases and ocular tissue homogenates indicated that 9-acyl...

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Detalhes bibliográficos
Main Authors: Cheng-Bennett, A, Chan, M F, Chen, G, Gac, T, Garst, M E, Gluchowski, C, Kaplan, L J, Protzman, C E, Roof, M B, Sachs, G
Formato: Artigo
Idioma:Inglês
Publicado em: 1994
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC504864/
https://ncbi.nlm.nih.gov/pubmed/7918269
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