Chargement en cours...

Evaluation of (+)-cyclaradine-5'-esters as prodrugs for (+)-cyclaradine in animals.

Both (+)-cyclaradine-5'-methoxyacetate (CM) and (+)-cyclaradine-5'-ethoxypropionate (CE) were converted to (+)-cyclaradine (C) in squirrel monkey and human sera at 37 degrees C. CE was more stable than CM. After oral administration (20 mg base equivalent per kg) of either CM or CE, no unch...

Description complète

Enregistré dans:
Détails bibliographiques
Auteurs principaux: Lim, J, Schwartz, J, Loebenberg, D, Miller, G H, Symchowicz, S, Lin, C
Format: Artigo
Langue:Inglês
Publié: 1987
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC174859/
https://ncbi.nlm.nih.gov/pubmed/3662479
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!