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Identification of early gene expression changes in primary cultured neurons treated with topoisomerase I poisons
Topoisomerase 1 (TOP1) poisons like camptothecin (CPT) are currently used in cancer chemotherapy but these compounds can have damaging, off-target effects on neurons leading to cognitive, sensory and motor deficits. To understand the molecular basis for the enhanced sensitivity of neurons to CPT, we...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | Biochem Biophys Res Commun |
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| Κύριοι συγγραφείς: | , , , , , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
2016
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5048596/ https://ncbi.nlm.nih.gov/pubmed/27641670 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2016.09.068 |
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