Identification of early gene expression changes in primary cultured neurons treated with topoisomerase I poisons

Topoisomerase 1 (TOP1) poisons like camptothecin (CPT) are currently used in cancer chemotherapy but these compounds can have damaging, off-target effects on neurons leading to cognitive, sensory and motor deficits. To understand the molecular basis for the enhanced sensitivity of neurons to CPT, we...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Biochem Biophys Res Commun
Main Authors: Rossi, Sharyn L., Lumpkin, Casey J., Harris, Ashlee W., Holbrook, Jennifer, Gentillon, Cinsley, McCahan, Suzanne M., Wang, Wenlan, Butchbach, Matthew E. R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5048596/
https://ncbi.nlm.nih.gov/pubmed/27641670
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2016.09.068
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados