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Structural Conservation and E2F Binding Specificity within the Retinoblastoma Pocket Protein Family
The human pocket proteins Rb, p107 and p130 are critical negative regulators of the cell cycle and contribute to tumor suppression. While strong structural conservation within the pocket protein family provides for some functional redundancy, important differences have been observed and may underlie...
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| Udgivet i: | J Mol Biol |
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| Main Authors: | , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2016
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5048593/ https://ncbi.nlm.nih.gov/pubmed/27567532 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2016.08.017 |
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