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Crystal Structure of the Unliganded Retinoblastoma Protein Pocket Domain
The retinoblastoma protein (Rb) regulates cell proliferation through its association with E2F transcription factors and other proteins. The Rb “pocket” domain primarily facilitates protein-protein interactions, and several structures of the pocket bound to E2F and tumorigenic viral proteins have bee...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3092862/ https://ncbi.nlm.nih.gov/pubmed/21491492 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prot.23007 |
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