लोड हो रहा है...
Structures of inactive retinoblastoma protein reveal multiple mechanisms for cell cycle control
Cyclin-dependent kinase (Cdk) phosphorylation of the Retinoblastoma protein (Rb) drives cell proliferation through inhibition of Rb complexes with E2F transcription factors and other regulatory proteins. We present the first structures of phosphorylated Rb that reveal the mechanism of its inactivati...
में बचाया:
| मुख्य लेखकों: | , , |
|---|---|
| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
Cold Spring Harbor Laboratory Press
2012
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3371405/ https://ncbi.nlm.nih.gov/pubmed/22569856 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.189837.112 |
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