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A Conserved Cysteine within the ATPase Domain of the Endoplasmic Reticulum Chaperone BiP is Necessary for a Complete Complement of BiP Activities

Among the amino acids, cysteine stands apart based on its highly reactive sulfur group. In general, cysteine is underrepresented in proteins. Yet when present, the features of cysteine often afford unique function. We have shown previously that a cysteine within the ATPase domain of yeast BiP (Kar2)...

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Détails bibliographiques
Publié dans:J Mol Biol
Auteurs principaux: Xu, Mengni, Marsh, Heather M., Sevier, Carolyn S.
Format: Artigo
Langue:Inglês
Publié: 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5048563/
https://ncbi.nlm.nih.gov/pubmed/27543005
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2016.08.011
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