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BiP, an endoplasmic reticulum chaperone, modulates the development of morphine antinociceptive tolerance

Morphine is a potent analgesic, but the molecular mechanism for tolerance formation after repeated use is not fully understood. Binding immunoglobulin protein (BiP) is an endoplasmic reticulum (ER) chaperone that is central to ER function. We examined knock-in mice expressing a mutant BiP with the r...

詳細記述

保存先:
書誌詳細
主要な著者: Dobashi, Tamae, Tanabe, Serabi, Jin, Hisayo, Mimura, Naoya, Yamamoto, Tatsuo, Nishino, Takashi, Aoe, Tomohiko
フォーマット: Artigo
言語:Inglês
出版事項: Blackwell Publishing Ltd 2010
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3822731/
https://ncbi.nlm.nih.gov/pubmed/19818092
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1582-4934.2009.00932.x
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