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BiP, an endoplasmic reticulum chaperone, modulates the development of morphine antinociceptive tolerance

Morphine is a potent analgesic, but the molecular mechanism for tolerance formation after repeated use is not fully understood. Binding immunoglobulin protein (BiP) is an endoplasmic reticulum (ER) chaperone that is central to ER function. We examined knock-in mice expressing a mutant BiP with the r...

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Detaylı Bibliyografya
Asıl Yazarlar: Dobashi, Tamae, Tanabe, Serabi, Jin, Hisayo, Mimura, Naoya, Yamamoto, Tatsuo, Nishino, Takashi, Aoe, Tomohiko
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Blackwell Publishing Ltd 2010
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3822731/
https://ncbi.nlm.nih.gov/pubmed/19818092
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1582-4934.2009.00932.x
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