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Synergistic antitumor activity of rapamycin and EF24 via increasing ROS for the treatment of gastric cancer
Mechanistic/mammalian target of rapamycin (mTOR) has emerged as a new potential therapeutic target for gastric cancer. Rapamycin and rapamycin analogs are undergoing clinical trials and have produced clinical responses in a subgroup of cancer patients. However, monotherapy with rapamycin at safe dos...
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| Veröffentlicht in: | Redox Biol |
|---|---|
| Hauptverfasser: | , , , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Elsevier
2016
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5048112/ https://ncbi.nlm.nih.gov/pubmed/27697670 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2016.09.006 |
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