EF24 induces ROS-mediated apoptosis via targeting thioredoxin reductase 1 in gastric cancer cells

Gastric cancer (GC) is one of the leading causes of cancer mortality in the world, and finding novel agents for the treatment of advanced gastric cancer is of urgent need. Diphenyl difluoroketone (EF24), a molecule having structural similarity to curcumin, exhibits potent anti-tumor activities by ar...

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Dettagli Bibliografici
Pubblicato in:Oncotarget
Autori principali: Zou, Peng, Xia, Yiqun, Chen, Weiqian, Chen, Xi, Ying, Shilong, Feng, Zhiguo, Chen, Tongke, Ye, Qingqing, Wang, Zhe, Qiu, Chenyu, Yang, Shulin, Liang, Guang
Natura: Artigo
Lingua:Inglês
Pubblicazione: Impact Journals LLC 2016
Soggetti:
Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4951270/
https://ncbi.nlm.nih.gov/pubmed/26919110
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.7633
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