EF24 induces ROS-mediated apoptosis via targeting thioredoxin reductase 1 in gastric cancer cells

Gastric cancer (GC) is one of the leading causes of cancer mortality in the world, and finding novel agents for the treatment of advanced gastric cancer is of urgent need. Diphenyl difluoroketone (EF24), a molecule having structural similarity to curcumin, exhibits potent anti-tumor activities by ar...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Zou, Peng, Xia, Yiqun, Chen, Weiqian, Chen, Xi, Ying, Shilong, Feng, Zhiguo, Chen, Tongke, Ye, Qingqing, Wang, Zhe, Qiu, Chenyu, Yang, Shulin, Liang, Guang
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4951270/
https://ncbi.nlm.nih.gov/pubmed/26919110
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.7633
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