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Conpair: concordance and contamination estimator for matched tumor–normal pairs
Motivation: Sequencing of matched tumor and normal samples is the standard study design for reliable detection of somatic alterations. However, even very low levels of cross-sample contamination significantly impact calling of somatic mutations, because contaminant germline variants can be incorrect...
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| Publié dans: | Bioinformatics |
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| Auteurs principaux: | , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Oxford University Press
2016
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5048070/ https://ncbi.nlm.nih.gov/pubmed/27354699 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btw389 |
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