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Genome-wide somatic variant calling using localized colored de Bruijn graphs
Reliable detection of somatic variations is of critical importance in cancer research. Here we present Lancet, an accurate and sensitive somatic variant caller, which detects SNVs and indels by jointly analyzing reads from tumor and matched normal samples using colored de Bruijn graphs. We demonstra...
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| Udgivet i: | Commun Biol |
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| Main Authors: | , , , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Publishing Group UK
2018
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6123722/ https://ncbi.nlm.nih.gov/pubmed/30271907 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s42003-018-0023-9 |
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