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Assessing Matched Normal and Tumor Pairs in Next-Generation Sequencing Studies
Next generation sequencing technology has revolutionized the study of cancers. Through matched normal-tumor pairs, it is now possible to identify genome-wide germline and somatic mutations. The generation and analysis of the data requires rigorous quality checks and filtering, and the current analyt...
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| Autores principales: | , , , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Public Library of Science
2011
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3060821/ https://ncbi.nlm.nih.gov/pubmed/21445261 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0017810 |
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