Overexpression of Ribosomal RNA in the Development of Human Cervical Cancer Is Associated with rDNA Promoter Hypomethylation

The ribosomal RNA (rRNA) gene encodes rRNA for protein synthesis. Aberrant expression of the rRNA gene has been generally observed in tumor cells and levels of its promoter methylation as an epigenetic regulator affect rRNA gene transcription. The possible relationship between expression and promote...

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Vydáno v:PLoS One
Hlavní autoři: Zhou, Hong, Wang, Yapei, Lv, Qiongying, Zhang, Juan, Wang, Qing, Gao, Fei, Hou, Haoli, Zhang, Hao, Zhang, Wei, Li, Lijia
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2016
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5047480/
https://ncbi.nlm.nih.gov/pubmed/27695092
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0163340
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