Overexpression of Ribosomal RNA in the Development of Human Cervical Cancer Is Associated with rDNA Promoter Hypomethylation

The ribosomal RNA (rRNA) gene encodes rRNA for protein synthesis. Aberrant expression of the rRNA gene has been generally observed in tumor cells and levels of its promoter methylation as an epigenetic regulator affect rRNA gene transcription. The possible relationship between expression and promote...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Zhou, Hong, Wang, Yapei, Lv, Qiongying, Zhang, Juan, Wang, Qing, Gao, Fei, Hou, Haoli, Zhang, Hao, Zhang, Wei, Li, Lijia
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5047480/
https://ncbi.nlm.nih.gov/pubmed/27695092
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0163340
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