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Overexpression of ribosomal RNA in prostate cancer is common but not linked to rDNA promoter hypomethylation

Alterations in nucleoli, including increased numbers, increased size, altered architecture and increased function are hallmarks of prostate cancer cells. The mechanisms that result in increased nucleolar size, number and function in prostate cancer have not been fully elucidated. The nucleolus is fo...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Uemura, M, Zheng, Q, Koh, C M, Nelson, W G, Yegnasubramanian, S, De Marzo, A M
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3298623/
https://ncbi.nlm.nih.gov/pubmed/21822302
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2011.319
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