E4F1-mediated control of pyruvate dehydrogenase activity is essential for skin homeostasis

The multifunctional protein E4 transcription factor 1 (E4F1) is an essential regulator of epidermal stem cell (ESC) maintenance. Here, we found that E4F1 transcriptionally regulates a metabolic program involved in pyruvate metabolism that is required to maintain skin homeostasis. E4F1 deficiency in...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Goguet-Rubio, Perrine, Seyran, Berfin, Gayte, Laurie, Bernex, Florence, Sutter, Anne, Delpech, Hélène, Linares, Laetitia Karine, Riscal, Romain, Repond, Cendrine, Rodier, Geneviève, Kirsh, Olivier, Touhami, Jawida, Noel, Jean, Vincent, Charles, Pirot, Nelly, Pavlovic, Guillaume, Herault, Yann, Sitbon, Marc, Pellerin, Luc, Sardet, Claude, Lacroix, Matthieu, Le Cam, Laurent
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2016
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5047149/
https://ncbi.nlm.nih.gov/pubmed/27621431
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1602751113
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados