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Acceleration of metallacycle-mediated alkyne–alkyne cross-coupling with TMSCl

Investigation of titanium-centered metallacycle-mediated cross-coupling between unsymmetrical internal alkynes has led to the discovery that TMSCl significantly accelerates the C–C bond forming event. We report a collection of results that compare the efficiency of this reaction employing Ti(Oi-Pr)(...

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Détails bibliographiques
Publié dans:Tetrahedron Lett
Auteurs principaux: Cassidy, James S., Mizoguchi, Haruki, Micalizio, Glenn C.
Format: Artigo
Langue:Inglês
Publié: 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5046837/
https://ncbi.nlm.nih.gov/pubmed/27713588
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tetlet.2016.07.045
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