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The hunt for a selective 17,20 lyase inhibitor; learning lessons from nature

Given prostate cancer is driven, in part, by its responsiveness to androgens, treatments historically employ methods for their removal from circulation. Approaches as crude as castration, and more recently blockade of androgen synthesis or receptor binding, are still of limited use long term, since...

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Podrobná bibliografie
Vydáno v:J Steroid Biochem Mol Biol
Hlavní autoři: Bird, Ian M, Abbott, David H
Médium: Artigo
Jazyk:Inglês
Vydáno: 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5046225/
https://ncbi.nlm.nih.gov/pubmed/27154414
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jsbmb.2016.04.021
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