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Steroid 17-Hydroxylase and 17,20-Lyase Deficiencies, Genetic and Pharmacologic
Steroid 17-hydroxylase 17,20-lyase (cytochrome P450c17, P450 17A1, CYP17A1) catalyzes two major reactions: steroid 17-hydroxylation followed by the 17,20-lyase reactions. The most severe mutations in the cognate CYP17A1 gene abrogate all activities and cause combined 17-hydroxylase/17,20-lyase defic...
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| Vydáno v: | J Steroid Biochem Mol Biol |
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| Hlavní autor: | |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2016
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4976049/ https://ncbi.nlm.nih.gov/pubmed/26862015 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jsbmb.2016.02.002 |
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