FoxO1 interacts with transcription factor EB and differentially regulates mitochondrial uncoupling proteins via autophagy in adipocytes

Mitochondrial uncoupling proteins (UCPs) are inducible and play an important role in metabolic and redox homeostasis. Recent studies have suggested that FoxO1 controls mitochondrial biogenesis and morphology, but it remains largely unknown how FoxO1 may regulate mitochondrial UCPs. Here we show that...

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Veröffentlicht in:Cell Death Discov
Hauptverfasser: Liu, Longhua, Tao, Zhipeng, Zheng, Louise D, Brooke, Joseph P, Smith, Cayleen M, Liu, Dongmin, Long, Yun Chau, Cheng, Zhiyong
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2016
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5046220/
https://ncbi.nlm.nih.gov/pubmed/27777789
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddiscovery.2016.66
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