Uncoupling FoxO3A mitochondrial and nuclear functions in cancer cells undergoing metabolic stress and chemotherapy

While aberrant cancer cell growth is frequently associated with altered biochemical metabolism, normal mitochondrial functions are usually preserved and necessary for full malignant transformation. The transcription factor FoxO3A is a key determinant of cancer cell homeostasis, playing a dual role i...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Celestini, Valentina, Tezil, Tugsan, Russo, Luciana, Fasano, Candida, Sanese, Paola, Forte, Giovanna, Peserico, Alessia, Lepore Signorile, Martina, Longo, Giovanna, De Rasmo, Domenico, Signorile, Anna, Gadaleta, Raffaella Maria, Scialpi, Natasha, Terao, Mineko, Garattini, Enrico, Cocco, Tiziana, Villani, Gaetano, Moschetta, Antonio, Grossi, Valentina, Simone, Cristiano
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5833443/
https://ncbi.nlm.nih.gov/pubmed/29445193
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-018-0336-0
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