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FoxO1 antagonist suppresses autophagy and lipid droplet growth in adipocytes

Obesity and related metabolic disorders constitute one of the most pressing heath concerns worldwide. Increased adiposity is linked to autophagy upregulation in adipose tissues. However, it is unknown how autophagy is upregulated and contributes to aberrant adiposity. Here we show a FoxO1-autophagy-...

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Détails bibliographiques
Publié dans:Cell Cycle
Auteurs principaux: Liu, Longhua, Zheng, Louise D., Zou, Peng, Brooke, Joseph, Smith, Cayleen, Long, Yun Chau, Almeida, Fabio A., Liu, Dongmin, Cheng, Zhiyong
Format: Artigo
Langue:Inglês
Publié: Taylor & Francis 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4968963/
https://ncbi.nlm.nih.gov/pubmed/27260854
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384101.2016.1192732
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