FoxO1 interacts with transcription factor EB and differentially regulates mitochondrial uncoupling proteins via autophagy in adipocytes

Mitochondrial uncoupling proteins (UCPs) are inducible and play an important role in metabolic and redox homeostasis. Recent studies have suggested that FoxO1 controls mitochondrial biogenesis and morphology, but it remains largely unknown how FoxO1 may regulate mitochondrial UCPs. Here we show that...

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Detalhes bibliográficos
Publicado no:Cell Death Discov
Main Authors: Liu, Longhua, Tao, Zhipeng, Zheng, Louise D, Brooke, Joseph P, Smith, Cayleen M, Liu, Dongmin, Long, Yun Chau, Cheng, Zhiyong
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5046220/
https://ncbi.nlm.nih.gov/pubmed/27777789
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddiscovery.2016.66
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