Comparison of [(11)C]TZ1964B and [(18)F]MNI659 for PET imaging brain PDE10A in nonhuman primates

Phosphodiesterase 10A (PDE10A) inhibitors show therapeutic effects for diseases with striatal pathology. PET radiotracers have been developed to quantify in vivo PDE10A levels and target engagement for therapeutic interventions. The aim of this study was to compare two potent and selective PDE10A ra...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Pharmacol Res Perspect
मुख्य लेखकों: Liu, Hui, Jin, Hongjun, Yue, Xuyi, Han, Junbin, Yang, Hao, Flores, Hubert, Su, Yi, Alagille, David, Perlmutter, Joel S., Tamagnan, Gilles, Tu, Zhude
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: John Wiley and Sons Inc. 2016
विषय:
Original Articles
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC5045939/
https://ncbi.nlm.nih.gov/pubmed/27713824
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prp2.253
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