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Comparison of [(11)C]TZ1964B and [(18)F]MNI659 for PET imaging brain PDE10A in nonhuman primates

Phosphodiesterase 10A (PDE10A) inhibitors show therapeutic effects for diseases with striatal pathology. PET radiotracers have been developed to quantify in vivo PDE10A levels and target engagement for therapeutic interventions. The aim of this study was to compare two potent and selective PDE10A ra...

詳細記述

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書誌詳細
出版年:Pharmacol Res Perspect
主要な著者: Liu, Hui, Jin, Hongjun, Yue, Xuyi, Han, Junbin, Yang, Hao, Flores, Hubert, Su, Yi, Alagille, David, Perlmutter, Joel S., Tamagnan, Gilles, Tu, Zhude
フォーマット: Artigo
言語:Inglês
出版事項: John Wiley and Sons Inc. 2016
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5045939/
https://ncbi.nlm.nih.gov/pubmed/27713824
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prp2.253
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