FKBP51 Null Mice Are Resistant to Diet-Induced Obesity and the PPARγ Agonist Rosiglitazone

FK506-binding protein-51 (FKBP51) is a molecular cochaperone recently shown to be a positive regulator of peroxisome proliferator-activated receptor (PPAR)γ, the master regulator of adipocyte differentiation and function. In cellular models of adipogenesis, loss of FKBP51 not only reduced PPARγ acti...

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Dettagli Bibliografici
Pubblicato in:Endocrinology
Autori principali: Stechschulte, Lance A., Qiu, Bin, Warrier, Manya, Hinds, Terry D., Zhang, Man, Gu, Hao, Xu, Yuxue, Khuder, Saja S., Russo, Lucia, Najjar, Sonia M., Lecka-Czernik, Beata, Yong, Weidong, Sanchez, Edwin R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Endocrine Society 2016
Soggetti:
Original Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5045506/
https://ncbi.nlm.nih.gov/pubmed/27442117
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2015-1996
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