Protein Phosphatase PP5 Controls Bone Mass and the Negative Effects of Rosiglitazone on Bone through Reciprocal Regulation of PPARγ (Peroxisome Proliferator-activated Receptor γ) and RUNX2 (Runt-related Transcription Factor 2)

Peroxisome proliferator-activated receptor γ (PPARγ) and runt-related transcription factor 2 (RUNX2) are key regulators of mesenchymal stem cell (MSC) differentiation toward adipocytes and osteoblasts, respectively. Post-translational modifications of these factors determine their activities. Dephos...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Stechschulte, Lance A., Ge, Chunxi, Hinds, Terry D., Sanchez, Edwin R., Franceschi, Renny T., Lecka-Czernik, Beata
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2016
Assuntos:
Gene Regulation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5114402/
https://ncbi.nlm.nih.gov/pubmed/27687725
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.752493
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