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Partial Agonist, Telmisartan, Maintains PPARγ Serine 112 Phosphorylation, and Does Not Affect Osteoblast Differentiation and Bone Mass

Peroxisome proliferator activated receptor gamma (PPARγ) controls both glucose metabolism and an allocation of marrow mesenchymal stem cells (MSCs) toward osteoblast and adipocyte lineages. Its activity is determined by interaction with a ligand which directs posttranscriptional modifications of PPA...

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Autors principals: Kolli, Vipula, Stechschulte, Lance A., Dowling, Abigail R., Rahman, Sima, Czernik, Piotr J., Lecka-Czernik, Beata
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4014504/
https://ncbi.nlm.nih.gov/pubmed/24810249
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0096323
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