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PPARγ2 NUCLEAR RECEPTOR CONTROLS MULTIPLE REGULATORY PATHWAYS OF OSTEOBLAST DIFFERENTIATION FROM MARROW MESENCHYMAL STEM CELLS
Rosiglitazone (Rosi), a member of the thiazolidinedione class of drugs used to treat type 2 diabetes, activates the adipocyte-specific transcription factor peroxisome proliferator-activated receptor gamma (PPARγ). This activation causes bone loss in animals and humans, at least in part due to suppre...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2009
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2745312/ https://ncbi.nlm.nih.gov/pubmed/19115254 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcb.21994 |
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