PPARγ2 NUCLEAR RECEPTOR CONTROLS MULTIPLE REGULATORY PATHWAYS OF OSTEOBLAST DIFFERENTIATION FROM MARROW MESENCHYMAL STEM CELLS

Rosiglitazone (Rosi), a member of the thiazolidinedione class of drugs used to treat type 2 diabetes, activates the adipocyte-specific transcription factor peroxisome proliferator-activated receptor gamma (PPARγ). This activation causes bone loss in animals and humans, at least in part due to suppre...

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Hlavní autoři: Shockley, Keith R., Lazarenko, Oxana P., Czernik, Piotr J., Rosen, Clifford J., Churchill, Gary A., Lecka-Czernik, Beata
Médium: Artigo
Jazyk:Inglês
Vydáno: 2009
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2745312/
https://ncbi.nlm.nih.gov/pubmed/19115254
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcb.21994
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