Increased liver carcinogenesis and enrichment of stem cell properties in livers of Dickkopf 2 (Dkk2) deleted mice

Dkk2 a antagonist of the Wnt/β-catenin-signaling pathway was shown to be silenced in diverse cancers. More recent data indicate that Dkk family members may also possess functions independent of Wnt-signaling during carcinogenesis. The detailed biological function of Dkks and its relevance for liver...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Maass, Thorsten, Marquardt, Jens, Lee, Ju-Seog, Krupp, Markus, Scholz-Kreisel, Peter, Mogler, Carolin, Schirmacher, Peter, Müller, Martina, Westphal, Heiner, Galle, Peter R., Teufel, Andreas
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2015
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5045365/
https://ncbi.nlm.nih.gov/pubmed/25826080
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.3293
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