Translating bioinformatics in oncology: guilt-by-profiling analysis and identification of KIF18B and CDCA3 as novel driver genes in carcinogenesis

Motivation: Co-regulated genes are not identified in traditional microarray analyses, but may theoretically be closely functionally linked [guilt-by-association (GBA), guilt-by-profiling]. Thus, bioinformatics procedures for guilt-by-profiling/association analysis have yet to be applied to large-sca...

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Publicat a:Bioinformatics
Autors principals: Itzel, Timo, Scholz, Peter, Maass, Thorsten, Krupp, Markus, Marquardt, Jens U., Strand, Susanne, Becker, Diana, Staib, Frank, Binder, Harald, Roessler, Stephanie, Wang, Xin Wei, Thorgeirsson, Snorri, Müller, Martina, Galle, Peter R., Teufel, Andreas
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2015
Matèries:
Original Papers
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4287940/
https://ncbi.nlm.nih.gov/pubmed/25236463
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btu586
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