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Dkk1 and Dkk2 Regulate Epicardial Specification during Mouse Heart Development

BACKGROUND: Dkk1 and Dkk2 interact with LRP5 and LRP6 to modulate canonical Wnt signaling during development, and are known to be expressed in the developing heart. However, a loss-of-function mutation in either gene by itself produces no discernable heart phenotype. METHODS: Using standard husbandr...

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Hlavní autoři: Phillips, Matthew D., Mukhopadhyay, Mahua, Poscablo, M. Cristina, Westphal, Heiner
Médium: Artigo
Jazyk:Inglês
Vydáno: 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2916964/
https://ncbi.nlm.nih.gov/pubmed/20439124
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijcard.2010.04.007
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