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Dkk1 and Dkk2 Regulate Epicardial Specification during Mouse Heart Development
BACKGROUND: Dkk1 and Dkk2 interact with LRP5 and LRP6 to modulate canonical Wnt signaling during development, and are known to be expressed in the developing heart. However, a loss-of-function mutation in either gene by itself produces no discernable heart phenotype. METHODS: Using standard husbandr...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2916964/ https://ncbi.nlm.nih.gov/pubmed/20439124 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijcard.2010.04.007 |
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