Heme oxygenase-1 nuclear translocation regulates bortezomib-induced cytotoxicity and mediates genomic instability in myeloma cells

Multiple myeloma (MM) is a clonal B-cell malignancy characterized by an accumulation of clonal plasma cells in the bone marrow leading to bone destruction and bone marrow failure. Several molecular mechanisms underlie chemoresistance among which heme oxygenase-1 (HO-1) could play a major role. The a...

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Detaylı Bibliyografya
Yayımlandı:Oncotarget
Asıl Yazarlar: Tibullo, Daniele, Barbagallo, Ignazio, Giallongo, Cesarina, Vanella, Luca, Conticello, Concetta, Romano, Alessandra, Saccone, Salvatore, Godos, Justyna, Di Raimondo, Francesco, Li Volti, Giovanni
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Impact Journals LLC 2016
Konular:
Research Paper
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5045362/
https://ncbi.nlm.nih.gov/pubmed/26930712
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.7563
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