Bortezomib modulates CHIT1 and YKL40 in monocyte-derived osteoclast and in myeloma cells

Osteolytic bone disease is a common manifestation of multiple myeloma (MM) that leads to progressive skeleton destruction and is the most severe cause of morbidity in MM patients. It results from increased osteolytic activity and decrease osteoblastic function. Activation of mammalian chitinases chi...

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Опубликовано в: :Front Pharmacol
Главные авторы: Tibullo, Daniele, Di Rosa, Michelino, Giallongo, Cesarina, La Cava, Piera, Parrinello, Nunziatina L., Romano, Alessandra, Conticello, Concetta, Brundo, Maria V., Saccone, Salvatore, Malaguarnera, Lucia, Di Raimondo, Francesco
Формат: Artigo
Язык:Inglês
Опубликовано: Frontiers Media S.A. 2015
Предметы:
Pharmacology
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4604315/
https://ncbi.nlm.nih.gov/pubmed/26528182
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2015.00226
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