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Bortezomib modulates CHIT1 and YKL40 in monocyte-derived osteoclast and in myeloma cells

Osteolytic bone disease is a common manifestation of multiple myeloma (MM) that leads to progressive skeleton destruction and is the most severe cause of morbidity in MM patients. It results from increased osteolytic activity and decrease osteoblastic function. Activation of mammalian chitinases chi...

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Detalhes bibliográficos
Publicado no:Front Pharmacol
Main Authors: Tibullo, Daniele, Di Rosa, Michelino, Giallongo, Cesarina, La Cava, Piera, Parrinello, Nunziatina L., Romano, Alessandra, Conticello, Concetta, Brundo, Maria V., Saccone, Salvatore, Malaguarnera, Lucia, Di Raimondo, Francesco
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4604315/
https://ncbi.nlm.nih.gov/pubmed/26528182
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2015.00226
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