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Bortezomib modulates CHIT1 and YKL40 in monocyte-derived osteoclast and in myeloma cells
Osteolytic bone disease is a common manifestation of multiple myeloma (MM) that leads to progressive skeleton destruction and is the most severe cause of morbidity in MM patients. It results from increased osteolytic activity and decrease osteoblastic function. Activation of mammalian chitinases chi...
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| Publié dans: | Front Pharmacol |
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| Auteurs principaux: | , , , , , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Frontiers Media S.A.
2015
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4604315/ https://ncbi.nlm.nih.gov/pubmed/26528182 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2015.00226 |
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