Inhibition of TLR4 Signaling Affects Mitochondrial Fitness and Overcomes Bortezomib Resistance in Myeloma Plasma Cells

Multiple myeloma (MM) is a B-cell malignancy requiring inflammatory microenvironment signals for cell survival and proliferation. Despite improvements in pharmacological tools, MM remains incurable mainly because of drug resistance. The present study aimed to investigate the implication of Toll-like...

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Publicado en:Cancers (Basel)
Main Authors: Giallongo, Cesarina, Tibullo, Daniele, Puglisi, Fabrizio, Barbato, Alessandro, Vicario, Nunzio, Cambria, Daniela, Parrinello, Nunziatina Laura, Romano, Alessandra, Conticello, Concetta, Forte, Stefano, Parenti, Rosalba, Amorini, Angela Maria, Lazzarino, Giuseppe, Li Volti, Giovanni, Palumbo, Giuseppe Alberto, Di Raimondo, Francesco
Formato: Artigo
Idioma:Inglês
Publicado: MDPI 2020
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7463509/
https://ncbi.nlm.nih.gov/pubmed/32707760
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12081999
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