Five birds, one stone: Neutralization of α-hemolysin and 4 bi-component leukocidins of Staphylococcus aureus with a single human monoclonal antibody

Staphylococcus aureus is a major human pathogen associated with high mortality. The emergence of antibiotic resistance and the inability of antibiotics to counteract bacterial cytotoxins involved in the pathogenesis of S. aureus call for novel therapeutic approaches, such as passive immunization wit...

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Main Authors: Rouha, Harald, Badarau, Adriana, Visram, Zehra C, Battles, Michael B, Prinz, Bianka, Magyarics, Zoltán, Nagy, Gábor, Mirkina, Irina, Stulik, Lukas, Zerbs, Manuel, Jägerhofer, Michaela, Maierhofer, Barbara, Teubenbacher, Astrid, Dolezilkova, Ivana, Gross, Karin, Banerjee, Srijib, Zauner, Gerhild, Malafa, Stefan, Zmajkovic, Jakub, Maier, Sabine, Mabry, Robert, Krauland, Eric, Wittrup, K Dane, Gerngross, Tillman U, Nagy, Eszter
Formáid: Artigo
Teanga:Inglês
Foilsithe: Taylor & Francis 2014
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Reports
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5045134/
https://ncbi.nlm.nih.gov/pubmed/25523282
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/19420862.2014.985132
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