Five birds, one stone: Neutralization of α-hemolysin and 4 bi-component leukocidins of Staphylococcus aureus with a single human monoclonal antibody

Staphylococcus aureus is a major human pathogen associated with high mortality. The emergence of antibiotic resistance and the inability of antibiotics to counteract bacterial cytotoxins involved in the pathogenesis of S. aureus call for novel therapeutic approaches, such as passive immunization wit...

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Udgivet i:MAbs
Main Authors: Rouha, Harald, Badarau, Adriana, Visram, Zehra C, Battles, Michael B, Prinz, Bianka, Magyarics, Zoltán, Nagy, Gábor, Mirkina, Irina, Stulik, Lukas, Zerbs, Manuel, Jägerhofer, Michaela, Maierhofer, Barbara, Teubenbacher, Astrid, Dolezilkova, Ivana, Gross, Karin, Banerjee, Srijib, Zauner, Gerhild, Malafa, Stefan, Zmajkovic, Jakub, Maier, Sabine, Mabry, Robert, Krauland, Eric, Wittrup, K Dane, Gerngross, Tillman U, Nagy, Eszter
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 2014
Fag:
Reports
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5045134/
https://ncbi.nlm.nih.gov/pubmed/25523282
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/19420862.2014.985132
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